Overall, very good. Just some minor clarifications needed.
If multiple Response cards are played by different players, how are they resolved?
Monsters: Do all Monsters do one damage? Does any Weapon defeat any Monster?
"In your turn" sounds odd. "On your turn" would be more common.
I think the turn actions could be reworded to be more clear. Basically there are three cases: you start the turn with no cards, in which case you just draw a card; you have no cards you can or want to play, in which case you discard a card; or you play a card.
If you are dead, do you need a specific "raise dead" card, or does any card that heals damage revive you?