The "Experience" header doesn't quite tell me what this section is about. It might make more sense to call this whole section "Ways to Play". That would also let you drop the subhead and give the spread a little more whitespace. The four modes themselves are clearly described.
The How to Play Overview might benefit from mentioning scoring as part of making a match. It's covered on the next page, but I did pause during the overview and wonder, "So how do I score points? Do the Black cards trigger scoring or something?" The White explainer's explanation of the page is a little redundant, so you might be able to re-deploy him to emphasize where the scoring opportunity is.
In the White Cards play example, you note that "You can also make a match using 3 White cards" etc. That's a new rule, and not part of the example, so you might want to separate it from the example text so player's don't miss it.
The "Special - Black Cards" subsection doesn't quite flow with the rest of the logic in the Rules section. You're treating it as a separate item, when it's really an elaboration on the previous "Play a Black Card" rule. You might want to remove the subhead so the two images flow together as one rule. This will also make it easier to see that "Pass on Your Turn" is a different action.
I'm not sure you need the "cards in hand cost points" reminder in the Game Over subsection. Players already have plenty of incentive to empty their hands. If you do include it, you might want to make it more of a strategy tip: "Cards left in your hand cost points at the end of the game cost points, so try to get ride of them!"
I love the world-building in the characters section, especially the little soap opera of Indigo. Totally unnecessary but totally awesome.
Once the Yellow player has looked at a hand, is Yellow's card switch power a "must" or a "may"? In general, must the powers be used when triggered, and must all steps of a power be taken if it's possible to do so? (There are very few cases where you wouldn't want to use these powers, but it might come up occasionally with the powers that trade cards from the hand.)